Thermo Fisher Scientific PTGER2 Recombinant Rabbit Monoclonal Antibody (ARC1393)
PTGER2 단백질을 표적하는 Thermo Fisher의 재조합 토끼 모노클로날 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. 높은 특이성과 재현성을 제공하며, 인간·마우스·랫트 시료에 반응합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific PTGER2 Recombinant Rabbit Monoclonal Antibody (ARC1393)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:6,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1393 |
| Immunogen | Synthetic peptide corresponding to amino acids 259–358 of human PGE receptor EP2 (PTGER2) (UniProt P43116) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849650 |
Product Specific Information
Immunogen sequence:
ETDHLILLAI MTITFAVCSL PFTIFAYMNE TSSRKEKWDL QALRFLSINS IIDPWVFAIL RPPVLRLMRS VLCCRISLRT QDATQTSCST QSDASKQADL
Target Information
Prostaglandins are produced by the metabolism of arachidonic acid. Prostaglandin E2 (PGE2) is one of five physiologically significant prostanoids. Its wide range of effects on immune, endocrine, cardiovascular, renal, and reproductive systems—as well as smooth muscle—are mediated through EP receptors (EP1–EP4).
EP2 receptors are 358 amino acid G-protein coupled receptors that stimulate adenylyl cyclase via Gs coupling and do not undergo PGE2-induced internalization. They are mainly localized in lung, placental, and smooth muscle tissues, playing important roles in neural functions and inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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