Thermo Fisher Scientific TCR V alpha 12.1 Monoclonal Antibody (6D6.6)
Thermo Fisher Scientific의 TCR V alpha 12.1 Monoclonal Antibody (6D6.6)은 인간 및 랫트 반응성을 가진 단클론 항체로, 다양한 면역학적 분석(WB, IHC, Flow Cytometry 등)에 사용됩니다. Protein G로 정제된 액상 형태이며, 연구용으로 TCR 관련 면역 반응 연구에 적합합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Flow Cytometry (Flow) | 1–2 µg/test | View 5 publications |
| Immunoprecipitation (IP) | Assay-dependent | - |
| T-Cell Activation (TCA) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6D6.6 |
| Immunogen | Human TCR V alpha 12.1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.5% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_223507 |
Additional Formats
Target Information
T cell receptors (TCRs) play a crucial role in distinguishing foreign peptides from self-peptides presented by MHC class II molecules, which is essential for adaptive immune responses. Recognition of self-peptides by TCRs has been linked to autoimmune diseases, while mutant self-peptides are associated with tumors. Engagement of TCRs by bacterial superantigens can lead to toxic shock syndrome. Autoantibodies to V beta segments of TCRs have been found in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), potentially serving as a compensatory immune mechanism.
Most human T cells express TCR alpha-beta and either CD4 or CD8 molecules (single positive, SP). A smaller subset lacks both (double negative, DN), which may increase in certain autoimmune or immunodeficiency disorders. Gamma-delta T cells, mainly found in epithelial tissues, exhibit less TCR diversity and distinct antigen recognition, with subsets showing antitumor and immunoregulatory activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific TCR V beta 5b Monoclonal Antibody (W112), FITC
776,200원
Thermo Fisher Scientific
Thermo Fisher Scientific TCR delta Monoclonal Antibody (TS-1), FITC
716,600원
Thermo Fisher Scientific
Thermo Fisher Scientific TCR V alpha 12.1 Monoclonal Antibody (6D6.6)
710,700원
Thermo Fisher Scientific
Thermo Fisher Scientific TCR V delta 1 Monoclonal Antibody (TS8.2)
712,600원
Thermo Fisher Scientific
Thermo Fisher Scientific TCR V beta 8b Monoclonal Antibody (MX-6)
607,100원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|