Thermo Fisher Scientific GPIP137 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GPIP137. Recombinant protein control fragment (Product #RP-90904). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPIP137,uniProtId:Q14444-1,ncbiNodeId:9606,antigenRange:214-349,antigenLength:709,antigenImageFileName:PA5-53733_GPIP137_Q14444-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53733_GPIP137_Q14444-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642143

Product Specific Information

Immunogen sequence: LWDLLEGKEK PVCGTTYKVL KEIVERVFQS NYFDSTHNHQ NGLCEEEEAA SAPAVEDQVP EAEPEPAEEY TEQSEVESTE YVNRQFMAET QFTSGEKEQV DEWTVETVEV VNSLQQQPQA ASPSVPEPHS LTPVAQ

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.

Target Information

GPIP137 regulates the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation/migration in multiple cell types. It binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, GPIP137 binds to several mRNAs associated with RNA granules including BDNF, CAMK2A, CREB1, MAP2, NTRK2, mRNAs, GRIN1, and KPNB1 mRNAs.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.