
Thermo Fisher Scientific GPIP137 Polyclonal Antibody
Thermo Fisher Scientific의 GPIP137 폴리클로날 항체로, 인간 GPIP137 단백질을 표적으로 합니다. WB, IHC(P), ICC/IF 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되었으며, 0.1 mg/mL 농도의 액상 형태. 연구용으로만 사용 가능.
- 카탈로그번호
- PA553733
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GPIP137. Recombinant protein control fragment (Product #RP-90904). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642143 |
Product Specific Information
Immunogen sequence:
LWDLLEGKEK PVCGTTYKVL KEIVERVFQS NYFDSTHNHQ NGLCEEEEAA SAPAVEDQVP EAEPEPAEEY TEQSEVESTE YVNRQFMAET QFTSGEKEQV DEWTVETVEV VNSLQQQPQA ASPSVPEPHS LTPVAQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 97%
- Rat: 96%
Target Information
GPIP137 regulates the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation/migration in multiple cell types.
It binds directly and selectively to MYC and CCND2 RNAs.
In neuronal cells, GPIP137 binds to several mRNAs associated with RNA granules including BDNF, CAMK2A, CREB1, MAP2, NTRK2, GRIN1, and KPNB1 mRNAs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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