Thermo Fisher Scientific BAIAP2L1 Polyclonal Antibody
BAIAP2L1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 면역형광에 적합합니다. 인간 시료에 반응하며, 항원 친화 정제 방식으로 제조되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–266 of BAIAP2L1 (Uniprot ID: Q9UHR4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.55 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153435 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2
- Predicted reactivity: Mouse (94%), Rat (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the IMD (IRSp53/MIM homology domain) family, subdivided into IRSp53-like and MIM-like groups based on the presence of the SH3 domain.
The encoded protein contains a conserved IMD (F-actin bundling domain) at the N-terminus and a canonical SH3 domain near the C-terminus, classifying it as IRSp53-like.
It acts as a substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac, participating in signal transduction pathways linking plasma membrane deformation with actin cytoskeleton remodeling.
Overexpression promotes actin assembly and membrane protrusions in mammalian cells and is essential for the formation of actin assembly complexes during EHEC pedestal formation.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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