Thermo Fisher Scientific BAIAP2L1 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, HeLa, HepG2
• Predicted reactivity: Mouse (94%), Rat (94%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a member of the IMD (IRSp53/MIM homology domain) family, subdivided into IRSp53-like and MIM-like groups based on the presence of the SH3 domain.
The encoded protein contains a conserved IMD (F-actin bundling domain) at the N-terminus and a canonical SH3 domain near the C-terminus, classifying it as IRSp53-like.
It acts as a substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac, participating in signal transduction pathways linking plasma membrane deformation with actin cytoskeleton remodeling.
Overexpression promotes actin assembly and membrane protrusions in mammalian cells and is essential for the formation of actin assembly complexes during EHEC pedestal formation.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.