Thermo Fisher Scientific COMMD10 Polyclonal Antibody
Thermo Fisher Scientific의 COMMD10 Polyclonal Antibody는 인간 및 마우스에 반응하며 WB, IHC, ICC/IF에 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 비결합 항체입니다. 단기 4°C, 장기 -20°C 보관 권장.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific COMMD10 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–202 of Human COMMD10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549341 |
Product Specific Information
- Recommended positive controls: A549, HeLa, HepG2, HCT116
- Predicted reactivity: Mouse (88%), Rat (89%), Pig (92%), Chicken (80%), Bovine (93%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The COMMD family represents a group of evolutionarily conserved proteins sharing a common COMM domain at their C-terminus, which mediates protein-protein interactions.
COMMD10 (COMM domain containing 10), also known as PTD002 or HSPC305, is a 202 amino acid protein belonging to the COMMD family and contains one COMM domain.
The COMMD10 gene maps to human chromosome 5, which spans approximately 181 million base pairs, comprising nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or the entire chromosome 5 is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
COMMD10 may modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes and may down-regulate activation of NF-kappa-B (PubMed:21778237).
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.