Thermo Fisher Scientific BTK Monoclonal Antibody (OTI10E10), Biotin, TrueMAB
BTK 단백질을 표적으로 하는 인간 반응성 마우스 모노클론 항체. Biotin으로 결합되어 ELISA 및 Luminex 분석에 적합. 고순도 친화 크로마토그래피로 정제되었으며 안정적인 PBS/BSA/글리세롤 버퍼에 보존. 연구용으로만 사용 가능.
- 카탈로그번호
- TA700513
- 판매단위
- pk
카탈로그
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Applications
ELISA (ELISA)
- Tested Dilution: 1:250–1:1,000
Luminex (LUM)
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10E10 |
| Immunogen | Full length human recombinant protein of human BTK produced in HEK293T cell |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders. BTK interacts with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9, which are critical molecules in both innate and adaptive immunity. BTK also interacts with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipopolysaccharide signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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