Thermo Fisher Scientific BTK Monoclonal Antibody (OTI12H4), Biotin, TrueMAB
BTK 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Biotin 결합 형식 제공. ELISA 및 Luminex 등 다양한 면역분석에 사용 가능. 높은 특이성과 재현성을 제공하며 연구용으로 적합. -20°C 보관 권장.
- 카탈로그번호
- TA700512
- 판매단위
- pk
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Applications
ELISA (ELISA)
- Tested Dilution: 1:250–1:1,000
Luminex (LUM)
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12H4 |
| Immunogen | Full length human recombinant protein of human BTK produced in HEK293T cell |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders. It interacts with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9, which are critical in innate and adaptive immunity. BTK also interacts with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting involvement in lipopolysaccharide signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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