Thermo Fisher Scientific CD44v6 Monoclonal Antibody (VFF-7), Biotin
CD44v6 단백질을 인식하는 Biotin 결합 단클론 항체. Western blot, IHC, 유세포분석 등 다양한 응용 가능. Rhesus monkey에서 검증됨. 4°C에서 보관하며 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
| Flow Cytometry (Flow) | Assay-dependent | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Rhesus monkey |
| Host / Isotype | Mouse / IgG1 |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Biotin, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VFF-7 |
| Immunogen | The epitope recognized by this antibody is a variant portion of CD44 encoded by exon v6. While the standard CD44 is observed to have ubiquitous expression, CD44 v6 expression appears to be limited to activated lymphocytes and macrophages. |
| Conjugate | Biotin |
| Available Formats | Unconjugated, FITC, Request custom conjugation |
| Form | Liquid |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
| RRID | AB_2536369 |
Target Information
CD44 cell surface antigen is a 100 kDa glycoprotein widely expressed on human leukocytes, white matter of the brain, and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues.
CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion, and migration. It also participates in various cellular functions including lymphocyte activation, recirculation, and homing.
CD44 expression may be up-regulated in some carcinomas, potentially relating to metastatic potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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