Thermo Fisher Scientific NME4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NME4 protein. Validated for Western blot applications. Supplied as a liquid, unconjugated form at 1 mg/mL concentration. Stored at -20°C with thimerosal preservative. For research use only.
- 카탈로그번호
- PA5117290
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Tested dilution 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human NME4. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901920 |
Product Specific Information
- Centrifuge briefly prior to opening.
Target Information
NME4 is a protein kinase that transfers a phosphate group from a donor molecule, typically the γ-phosphate of ATP, to an acceptor amino acid residue in a substrate protein. Through this mechanism, protein kinases mediate signal transduction in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell motility, apoptosis, and differentiation.
The protein kinase family includes over 500 gene products and is classified into eight major groups based on catalytic domain sequences. The AGC kinase group consists of 63 kinases, including PKA/PKG (cyclic nucleotide-regulated), PKC (phospholipid-dependent), RAC/Akt (related to PKA and PKC), ARK (G protein-coupled receptor kinases), and RSK (ribosomal S6 kinases).
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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