Thermo Fisher Scientific ERLIN2 Polyclonal Antibody
ERLIN2 단백질을 인식하는 Thermo Fisher Scientific의 goat 유래 polyclonal antibody. Western blot 및 IHC(Paraffin) 검증 완료. 인간 반응성, rat 예측 반응성. 고순도 액상 형태로 안정적 보관 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ERLIN2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (EDEPLETATKEN) corresponding to the C-terminus amino acids of ERLIN2 (aa 328–339) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980016 |
Product Specific Information
- Predicted to react with rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 2,000.
Target Information
ERLIN2, also named as C8orf2 and SPFH2, is a component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1.
It promotes sterol-accelerated ERAD of HMGCR, implicating an AMFR/gp78-containing ubiquitin ligase complex.
ERLIN2 is involved in regulation of cellular cholesterol homeostasis by regulating the SREBP signaling pathway.
The molecular weight of the ERLIN1/ERLIN2 complex is about 70 kDa.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.