Thermo Fisher Scientific Thyroglobulin Monoclonal Antibody (TG8.1)

Applications

Tested Dilution

Publications

ELISA (ELISA)

1-10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM

Class

Monoclonal

Type

Antibody

Clone

TG8.1

Immunogen

Purified human Thyroglobulin. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Thyroglobulin,uniProtId:P01266-1,ncbiNodeId:9606,antigenRange:1-2768,antigenLength:2768,antigenImageFileName:MA1-10595_Thyroglobulin_P01266-1_House_mouse.svg,antigenImageFileNamePDP:MA1-10595_Thyroglobulin_P01266-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.2 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1087812

Product Specific Information

MA1-10595 detects Thyroglobulin, specifically both T3 and T4, from human samples.

MA1-10595 has been successfully used in ELISA applications.

The MA1-10595 immunogen is purified human Thyroglobulin.

Target Information

The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.