Thermo Fisher Scientific TAGL2 Polyclonal Antibody
TAGL2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC, ICC, Flow Cytometry, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human TAGL2 (amino acids 51–160) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Transgelin (also designated SM22alpha) is abundantly expressed in smooth muscle cells. Transgelin-2 (SM22alpha homolog) is a homolog of transgelin and is also expressed in smooth muscle cells and peritoneal B-1 cells.
The human transgelin-2 gene (TAGLN2), located on chromosome 1q23.1–q25, encodes a 199 amino acid protein containing a calponin-like repeat and a calponin-homology (CH) domain.
Transgelin-2 may function similarly to transgelin. During embryogenesis, transgelin is expressed in smooth, cardiac, and skeletal muscle, but later restricted to vascular and visceral smooth muscle cells, with low expression in the heart.
Downregulation of transgelin has been observed in several transformed cell lines, suggesting its reduction may be an early indicator of cellular transformation.
Transgelin binds actin, inducing actin fiber gelation within minutes at a 1:6 actin monomer ratio.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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