Thermo Fisher Scientific EMAP II Polyclonal Antibody
Western blot, IHC, ICC, ELISA, IP 등 다양한 응용에 적합한 EMAP II 폴리클로날 항체. Rabbit IgG 기반으로 Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 PBS 버퍼에 보존제 미함유.
- 카탈로그번호
- PA5117774
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 1–5 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human EMAP-II/AIMP1 Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2902385 |
Target Information
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis and is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit associated with the multi-tRNA synthetase complex, modulating aminoacylation activity of tRNA synthetase in normal cells. This protein also stimulates inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene, and a pseudogene has been identified on chromosome 20.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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