Thermo Fisher Scientific HnRNP Q Recombinant Rabbit Monoclonal Antibody (JG35-72)
HnRNP Q 단백질을 인식하는 Thermo Fisher의 재조합 토끼 단클론 항체. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 고순도 Protein A 정제, 안정적 액상 형태로 제공. 인플라메이션 관련 mRNA 번역 조절 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JG35-72 |
| Immunogen | Synthetic peptide within Human hnRNP Q aa 574–623 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848643 |
Product Specific Information
Positive Control: K562, LOVO, SiHa, rat testis tissue, human thyroid gland tissue, human breast tissue, human kidney tissue.
Target Information
Heterogeneous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoforms 1–3 are associated with pre-mRNA, splicing intermediates, and mature mRNA complexes. Isoform 1 binds to apoB mRNA AU-rich sequences and is part of the APOB mRNA editosome complex, possibly modulating post-transcriptional C to U RNA-editing. May be involved in translationally coupled mRNA turnover and cytoplasmic mRNA decay mechanisms. Isoform 3 may participate in mRNA transport via vesicle interactions with synaptotagmins. Component of the GAIT complex mediating interferon-gamma-induced transcript-selective translation inhibition during inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- MA5-34735_HnRNP_Q_O60506-1_Rabbit.svg
- MA5-34735_HnRNP_Q_O60506-1_Rabbit_PDP.jpeg
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