Thermo Fisher Scientific DNL3 Polyclonal Antibody
인간 DNA Ligase III를 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제되었으며 1.0 mg/mL 농도의 액상 제품. TBS buffer에 0.09% sodium azide 포함, 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
- Publications: References
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 800 and 850 of human DNA Ligase III |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair, and recombination.
DNA Ligase III gene product migrates as a 100 kDa (α-form) protein in somatic tissues, is ubiquitously expressed, and complexes with XRCC-1 and a 97 kDa (β-form) protein that is found in testis.
DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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