Thermo Fisher Scientific RFC2 Monoclonal Antibody (OTI4E1), TrueMAB
RFC2 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Human 시료에 반응합니다. Western blot과 Flow cytometry에 적합하며, Lyophilized 형태로 제공됩니다. 고순도 Affinity chromatography 정제, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–234 of human RFC2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The RFC2 gene encodes a member of the activator 1 small subunits family. DNA polymerase delta and epsilon require accessory proteins such as PCNA and replication factor C (RFC) for elongation of primed DNA templates. RFC is a complex of five distinct subunits, and RFC2 encodes the 40 kDa subunit responsible for ATP binding and possibly promoting cell survival.
Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of RFC2 exists on chromosome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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