Thermo Fisher Scientific DUSP5 Monoclonal Antibody (OTI5H9), TrueMAB
DUSP5 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 적합. Human, Mouse, Rat 반응성. Lyophilized 형태로 제공되며 PBS buffer(8% trehalose) 포함. 연구용으로 ERK1 관련 신호전달 연구에 활용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 125–384 of human DUSP5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20 °C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The protein encoded by this gene belongs to the dual specificity protein phosphatase subfamily. These phosphatases deactivate their target kinases by dephosphorylating both phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase (MAPK) superfamily, which are associated with cellular proliferation and differentiation.
Different members of this family show distinct substrate specificities, tissue distribution, subcellular localization, and inducibility by extracellular stimuli.
This gene product inactivates ERK1, is expressed in various tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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