Thermo Fisher Scientific ACP6 Polyclonal Antibody
ACP6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P)에서 검증됨. Human 시료에 반응하며 항원 친화 크로마토그래피로 정제됨. PBS/glycerol 버퍼에 보관하며 -20°C에서 안정적 저장 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human acid phosphatase 6, lysophosphatidic acid phosphatase type 6 (ACP6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635894 |
Product Specific Information
The antibody detects endogenous levels of total ACP6 protein.
Target Information
Lysophosphatidic acid phosphatase type 6 (ACP6), also known as acid phosphatase-like protein 1 (ACPL1) or lysophosphatidic acid phosphatase (LPAP), is a 428 amino acid secreted enzyme that hydrolyzes lysophosphatidic acid to monoacylglycerol.
ACP6 is highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, and ovary, and exists as two isoforms due to alternative splicing.
The ACP6 gene is located on human chromosome 1, which spans approximately 260 million base pairs and represents about 8% of the human genome. Chromosome 1 is associated with several diseases, including Hutchinson-Gilford progeria (LMNA gene), Stickler syndrome, Parkinson’s disease, Gaucher disease, familial adenomatous polyposis, and Usher syndrome. Aberrations in chromosome 1 are also linked to multiple cancers such as head and neck cancer, malignant melanoma, and multiple myeloma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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