Thermo Fisher Scientific MAGEA10 Polyclonal Antibody
인간 MAGEA10 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에서 사용 가능. 항원 친화 크로마토그래피로 정제된 고농도 액상 항체. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunohistochemistry (IHC)
- Tested Dilution: Not specified
- Reference: 1 publication available
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to a region derived from internal residues of human melanoma antigen family A, 10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635897 |
Product Specific Information
The antibody detects endogenous levels of total MAGEA10 protein.
Target Information
MAGEA10 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50–80% sequence identity between each other.
The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls.
The MAGEA genes are expressed at high levels in a number of tumors of various histologic types, and are silent in normal tissues except for testis and placenta.
The MAGEA genes are clustered on chromosome Xq28 and may be implicated in some hereditary disorders, such as dyskeratosis congenita.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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