Thermo Fisher Scientific GTF2A2 Monoclonal Antibody (2B9)
GTF2A2 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체(2B9). Western blot 및 ELISA에 최적화되어 있으며, 인간 시료에 반응합니다. PBS(pH 7.4) 용액 형태로 제공되며, 보존제 무첨가. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B9 |
| Immunogen | GTF2A2 (AAH00287, 1–109 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MAYQLYRNTT LGNSLQESLD ELIQSQQITP QLALQVLLQF DKAINAALAQ RVRNRVNFRG SLNTYRFCDN VWTFVLNDVE FREVTELIKV DKVKIVACDG KNTGSNTTE
Target Information
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A) and the general initiation factors TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIG/TFIIJ, and TFIIH.
The first step involves recognition of the TATA element by the TATA-binding subunit (TBP) and may be regulated by TFIIA, a factor interacting with both TBP and TAF in TFIID.
TFIIA has 2 subunits (43 and 12 kDa) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kDa alpha subunit and a 19-kDa beta subunit encoded by GTF2A1, and a 12-kDa gamma subunit encoded by GTF2A2 (DeJong et al., 1995).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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