Thermo Fisher Scientific STAT2 Polyclonal Antibody
STAT2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에서 사용 가능. 인간 시료 반응성, 항원 친화 크로마토그래피로 정제. 연구용으로만 사용.
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Thermo Fisher Scientific STAT2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide of human STAT2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human hepatocellular carcinoma
- Cellular location: Cytoplasm, Nucleus
Target Information
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.
In response to interferon (IFN), STAT2 forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), acting as a transactivator but lacking direct DNA binding ability.
Transcription adaptor P300/CBP (EP300/CREBBP) interacts specifically with STAT2 and may play a role in blocking IFN-alpha response by adenovirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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