Thermo Fisher Scientific BRD2 Recombinant Rabbit Monoclonal Antibody (BL-167-2A2)
BRD2 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot, Flow cytometry, Immunoprecipitation에 사용 가능. 인간 및 마우스 반응성. HEK293 세포에서 발현된 IgG 형 항체. 연구용으로 4°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Flow Cytometry (Flow)
- Tested Dilution: 5 µL per 1 x 10^6 cells
Immunoprecipitation (IP)
- Tested Dilution: 20 µL per 1 mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BL-167-2A2 |
| Immunogen | Synthetic peptide representing a region between residues 675 and 725 of human bromodomain containing 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 40 µg/mL |
| Purification | Ion-exchange chromatography |
| Storage Buffer | BBS, pH 8.2, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
This gene encodes a transcriptional regulator belonging to the BET (bromodomains and extra terminal domain) family of proteins. It associates with transcription complexes and acetylated chromatin during mitosis, selectively binding to the acetylated lysine-12 residue of histone H4 via its two bromodomains.
The gene maps to the MHC class II region on chromosome 6p21.3, though sequence comparison suggests it is not involved in immune response.
It has been implicated in juvenile myoclonic epilepsy, a common adolescent-onset epilepsy. Multiple alternatively spliced variants have been described, though some full-length forms remain undetermined.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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