Thermo Fisher Scientific IL13 Polyclonal Antibody
Thermo Fisher Scientific IL13 Polyclonal Antibody는 돼지 IL-13 단백질에 특이적인 항체로, Western blot, ELISA, Immunoprecipitation 등에 사용됩니다. Rabbit IgG 폴리클로날 항체이며 Protein A로 정제되어 높은 순도와 안정성을 제공합니다.
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- 200-401-B55x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IL13 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| ELISA | 1:11,000 |
| Immunoprecipitation (IP) | 1.5–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Sheep, Pig |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length recombinant swine IL-13 protein raised in yeast. Protein-A purified antibody prepared from whole rabbit serum produced by repeated immunizations. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at 4°C prior to restoration.
- For extended storage, aliquot and freeze at -20°C or below.
- Avoid freeze/thaw cycles.
- Centrifuge if not clear after standing at room temperature.
- Stable for several weeks at 4°C as undiluted liquid.
- Dilute only prior to immediate use.
This antibody is specific for swine IL-13 protein. BLAST analysis indicates:
- 100% homology with swine IL-13 (immunizing sequence)
- 89–90% homology with IL-13 from sheep, dolphin, beluga, and bovine
- 83–88% with human and certain monkey IL-13
- 80–82% with dusky titi, macaque, baboon, mangabey, dog, llama, camel, and galago
- 75–78% with horse
- 67–72% with rat, mouse, and gerbil
Cross-reactivity with IL-13 from other sources has not been determined.
Target Information
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.
It regulates inflammatory and immune responses by down-regulating macrophage activity and inhibiting pro-inflammatory cytokine production.
IL-13 plays a role in allergen-induced asthma, B cell maturation and differentiation, up-regulates CD23 and MHC class II, and promotes IgE isotype switching.
Structurally, IL-13 resembles IL-3, IL-4, IL-5, and GM-CSF.
The IL-13 gene is located on chromosome 5q, close to IL4 within the cytokine gene cluster.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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