Thermo Fisher Scientific FGFR4 Monoclonal Antibody (7H1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:200-1:1,000

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

7H1

Immunogen

Purified recombinant extracellular fragment of human FGFR4 fused with hIgGFc tag expressed in HEK293 cell line.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_10985085

Product Specific Information

MA5-15500 targets FGFR4 in indirect ELISA, IF and WB applications and shows reactivity with Human samples.

The MA5-15500 immunogen is purified recombinant extracellular fragment of human FGFR4 fused with hIgGFc tag expressed in HEK293 cell line.

MA5-15500 detects FGFR4 which has a predicted molecular weight of approximately 87.9kDa.

Target Information

FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.