Thermo Fisher Scientific VNN1 Polyclonal Antibody
VNN1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 실험에 적합합니다. 고순도의 항원 친화 크로마토그래피로 정제되었으며, PBS와 50% glycerol buffer에 보관됩니다. 인간 시료에 반응하며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Vanin 1 (amino acids 389–497 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903998 |
Target Information
Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes. The GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells. Vanin-1 acts as a pantetheinase enzyme, catalyzing the hydrolysis of pantetheine for vitamin B5 recycling and generating the antioxidant cysteamine. As a membrane-bound enzyme, vanin-1 provides the main source of cysteamine under normal physiological conditions. In mice, vanin-1 is specifically expressed in male Sertoli cells of the developing testis, aiding in cell migration.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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