Thermo Fisher Scientific CD49c (Integrin alpha 3) Polyclonal Antibody
CD49c(Integrin alpha 3)에 특이적인 Thermo Fisher Scientific의 Goat Polyclonal Antibody. 인간 및 마우스 반응성, Western blot 검증 완료. 액상 형태로 0.5 mg/mL 농도, TBS(pH 7.3) 버퍼에 0.5% BSA 및 0.02% sodium azide 포함. 연구용으로만 사용.
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Thermo Fisher Scientific CD49c (Integrin alpha 3) Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-KSQPSETERLTDD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933878 |
Product Specific Information
- This antibody is expected to recognize reported isoform a (NP_002195.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
ITGA3 (Integrin alpha-3), also known as CD49C, VLA3, or GAPB3, is encoded by the ITGA3 gene in humans. It is an integrin alpha subunit and a member of the family of cell surface adhesion molecules.
ITGA3 is mapped to chromosome 17q21.33 and forms half of the alpha3beta1 integrin duplex, which plays a role in neural migration and corticogenesis together with the beta-1 subunit.
A functional link between DAB1 phosphorylation and ITGA3 signaling drives neuronal detachment from radial glial fibers. Expression of human ITGA3 increases virus infectivity in CHO cells.
ITGA3 contains 13 potential N-glycosylation sites, 2 cleavage sites, and 7 N-terminal repeating units characteristic of integrins. Recombinant ITGA3 is expressed as a 150-kD protein, matching the native protein in western blot analysis.
Usage
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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