Thermo Fisher Scientific CNGB3 Polyclonal Antibody
CNGB3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응합니다. IHC(P)에서 2–4 µg/mL 농도로 사용 가능하며, 액상 형태로 제공됩니다. 시각 신호전달 연구용으로 적합하며, -20°C에서 보관합니다.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 2–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-ESDDKPTEHYYR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933881 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as a second messenger. This protein can be activated by cGMP, leading to opening of the cation channel and depolarization of rod photoreceptors. It induces flickering channel gating, weakens outward rectification in the presence of extracellular calcium, increases sensitivity for L-cis diltiazem, and enhances cAMP efficiency of the channel when coexpressed with CNGA3. It is essential for the generation of light-evoked electrical responses in the red-, green-, and blue-sensitive cones.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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