Thermo Fisher Scientific CDKN2B Polyclonal Antibody
CDKN2B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western blot, IHC, ICC/IF, Flow Cytometry에 사용 가능하며, 고순도 Affinity chromatography로 정제되었습니다. 연구용으로만 사용됩니다.
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- PA5116445
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human p15 INK4b (aa 1–138) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 0.2% BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2901077 |
Product Specific Information
Positive controls:
Hela, SiHa, rat kidney tissue, human esophagus cancer tissue, human small intestine tissue, mouse liver tissue.
Target Information
The four known 15–19 kDa INK4 proteins (p15INK4b, p16INK4a, p18INK4c, and p19INK4d) bind and inhibit CDK4 and CDK6 but not other CDKs, such as cyclin E-Cdk2, cyclin A-Cdk2, and cyclin B-Cdk1.
Like the three D-type cyclins, the INK4 genes are expressed in distinct tissue-specific patterns, suggesting they are not strictly redundant.
p18INK4c is expressed during the G1 to S transition in the eukaryotic cell division cycle and is maximally induced as cells enter S-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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