Thermo Fisher Scientific LDOC1 Polyclonal Antibody
LDOC1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간 시료에 반응하며 IHC(P)에서 1:50~1:200 희석 사용. NF-κB 매개 전사 반응 연구 및 암 관련 유전자 발현 분석에 적합. 항원 친화 크로마토그래피로 정제됨.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the N-terminal of human leucine zipper, down-regulated in cancer 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635891 |
Product Specific Information
This antibody detects endogenous levels of total LDOC1 protein.
Target Information
LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by nuclear factor kappa B (NF-κB). The gene has been proposed as a tumor suppressor gene whose protein product may play an important role in the development and/or progression of certain cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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