Thermo Fisher Scientific RGS13 Polyclonal Antibody
Rabbit polyclonal antibody targeting RGS13 protein. Validated for Western blot applications. Recognizes synthetic peptide (AA 111-127). Suitable for research use only. Stored at -20°C, avoid freeze/thaw cycles.
- 카탈로그번호
- PA523111
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:250–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (AA 111–127, RNIQEPTETCFEEAQKI) of RGS13 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2540638 |
Target Information
RGS13 is the smallest member of the mammalian RGS (Regulators of G protein-signaling) family, which are structural and functional homologues of yeast SST2 and C. elegans egl-10 proteins.
RGS proteins attenuate G protein-mediated pathways by acting as GTPase-activating proteins (GAPs) for Ga subunits.
RGS13 is abundantly expressed in human tonsil, thymus, lung, lymph node, and spleen, and regulates Gai, Gaq, and Gas coupled signaling cascades.
It functions as a GTPase-activating protein for Gai and Gao, blocks MAPK activity induced by Gai- or Gaq-coupled receptors, and attenuates GTPase-deficient Gaq (GaqQL) mediated cAMP response element activation.
The human RGS13 gene is localized on chromosome 1q31.2.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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