Thermo Fisher Scientific RNF183 Polyclonal Antibody
인간 RNF183 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증됨. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol 버퍼에 보관. 세포자멸사 및 유비퀴틴화 연구에 적합.
- 카탈로그번호
- PA563466
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RNF183 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested dilution: Not specified
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RNF183. Recombinant protein control fragment (Product # RP-99866) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646650 |
Product Specific Information
Immunogen sequence:
ELEAECPVCW NPFNNTFHTP KMLDCCHSFC VECLAHLSLV TPARRRLLCP LCRQPTVLAS GQPVTDLPTD
Antigen sequence identity:
- Mouse: 97%
- Rat: 94%
Target Information
Acts as an E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (PubMed:29507230).
Triggers apoptosis in response to prolonged ER stress by mediating the polyubiquitination and subsequent proteasomal degradation of BCL2L1 (PubMed:29507230).
May collaborate with FATE1 to restrain BIK protein levels thus regulating apoptotic signaling (PubMed:26567849).
[Source: UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.