Thermo Fisher Scientific Cathepsin A Recombinant Rabbit Monoclonal Antibody (108)

Applications

ELISA

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates.
Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to rabbit immune repertoire

This antibody specifically recognizes Mouse Cathepsin A/CTSA.

Target Information

The cathepsin family includes diverse proteolytic enzymes classified into several protease types:

• Cysteine proteases: Cathepsins B, L, H, K, S, O
• Aspartyl proteases: Cathepsins D, E
• Serine proteases: Cathepsin G

Cathepsin A, a serine carboxypeptidase, forms a lysosomal complex with β-galactosidase (β-gal) and α-neuraminidase (Neu1), protecting them from intralysosomal proteolysis.
Deficiency of Cathepsin A leads to reduced β-gal and Neu1 activity.
The human Cathepsin A gene maps to chromosome 20q13.12, and mutations cause galactosialidosis, a lysosomal storage disorder.

For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.