Thermo Fisher Scientific MAGEH1 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MAGEH1 (NP_054780.2, 1 a.a. approximately 219 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MAGEH1,uniProtId:Q9H213-1,ncbiNodeId:9606,antigenRange:1-219,antigenLength:219,antigenImageFileName:H00028986-D01P_MAGEH1_Q9H213-1_Rabbit.svg,antigenImageFileNamePDP:H00028986-D01P_MAGEH1_Q9H213-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MPRGRKSRRR RNARAAEENR NNRKIQASEA SETPMAASVV ASTPEDDLSG PEEDPSTPEE ASTTPEEASS TAQAQKPSVP RSNFQGTKKS LLMSILALIF IMGNSAKEAL VWKVLGKLGM QPGRQHSIFG DPKKIVTEEF VRRGYLIYKP VPRSSPVEYE FFWGPRAHVE SSKLKVMHFV ARVRNRCSKD WPCNYDWDSD DDAEVEAILN SGARGYSAP

Target Information

Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGEH1 is not fully elucidated, it may play a role in embryonal development and tumor transformation or aspects of tumor progression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.