Thermo Fisher Scientific ARHGEF10 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ARHGEF10 (AAH40474.1, 1 a.a. approximately 380 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ARHGEF10,uniProtId:O15013-1,ncbiNodeId:9606,antigenRange:1-1369,antigenLength:1369,antigenImageFileName:H00009639-B01P_ARHGEF10_O15013-1_House_mouse.svg,antigenImageFileNamePDP:H00009639-B01P_ARHGEF10_O15013-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MENPEEAIYD DVPRENSDSE PDEMIYDDVE NGDEGGNSSL EYGWSSSEFE SYEEQSDSEC KNGIPRSFLR SNHKKQMQKL VKAAKDGTKD GLERTRAAVK RGRSFIRTKS LIAQDHRSSL EEEQNLFIDV DCKHPEAILT PMPEGLSQQQ VVRRYILGSV VDSEKNYVDA LKRILEQYEK PLSEMEPKVL SERKLKTVFY RVKEILQCHS LFQIALASRV SEWDSVEMIG VVFVASFSKS MVLDAYSEYV NNFSTAVAVL KKTCATKPAF LEFLKQEQEA SPDRTTLYSL MMKPIQRFPQ FILLLQDMLK NTSKGHPDRL PLQMALTELE TLAEKLNERK RDADQRCEVK QIAKAINERY LNKVERGFLQ LYSKIIFALC

Target Information

This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.