Thermo Fisher Scientific SAP102 Polyclonal Antibody
SAP102 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간·생쥐·랫트 반응성 검증됨. Western blot 및 IHC에 사용 가능. Lyophilized 형태로 제공되며, 장기 보관 시 -20°C 권장. 신경 시냅스 단백질 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous PubMed (Misc)
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from C-terminal region of human SAP102 (DLG3) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Peptide shares 95% identity with rat and mouse sequences.
- Specificity: SAP102.
Target Information
Synapse-Associated Protein 102 (SAP102) is a plasma membrane-associated protein found in synaptic junctions. It contains three PDZ domains, an SH3 domain, and a GuK domain.
SAP102 plays a role in receptor and channel clustering, contributing to neuronal plasticity. It interacts with NMDA receptors and shaker-type potassium channels at CNS synapses.
Other neuronal proteins sharing the T/SXV motif may bind SAP102 via PDZ domains. Neuronal nitric oxide synthase (nNOS) also associates with SAP102 through PDZ-PDZ interaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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