
Thermo Fisher Scientific LMTK3 Polyclonal Antibody
LMTK3 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체. Western blot에 적합하며, Mouse에서 반응. Affinity chromatography로 정제되고 PBS/sucrose buffer에 보관. ESR1 관련 신호전달 연구에 활용 가능.
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Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of Mouse Lmtk3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2884779 |
Product Specific Information
- Immunogen sequence: RGLLKSPRAA DEPEDSELER KRKMVSFHGD VTVYLFDQET PTNELSVQGT
- Storage guidance:
- Short term: 2–8°C up to 1 week
- Long term: -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology: Cow: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 93%; Pig: 100%
Target Information
Protein kinase that phosphorylates ESR1 in vitro and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway, decreasing PKC activity and AKT phosphorylation, thereby enhancing FOXO3 binding to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804).
Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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