Thermo Fisher Scientific ZBTB17 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ZBTB17. Recombinant protein control fragment (Product #RP-100705). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZBTB17,uniProtId:Q13105-1,ncbiNodeId:9606,antigenRange:84-225,antigenLength:803,antigenImageFileName:PA5-52208_ZBTB17_Q13105-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52208_ZBTB17_Q13105-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649760

Product Specific Information

Immunogen sequence: LSPENVDDVL AVATFLQMQD IITACHALKS LAEPATSPGG NAEALATEGG DKRAKEEKVA TSTLSRLEQA GRSTPIGPSR DLKEERGGQA QSAASGAEQT EKADAPREPP PVELKPDPTS GMAAAEAEAA LSESSEQEME VE

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 76%.

Target Information

Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.