Thermo Fisher Scientific Importin 8 Polyclonal Antibody
Human 시료에 반응하는 Importin 8 단백질에 대한 Goat Polyclonal 항체. IHC(P)에서 4–6 µg/mL 농도로 사용 가능. Isoform 1 및 2를 인식하며, Peptide ELISA에서 높은 민감도 확인. TBS buffer(pH 7.3) 내 0.5% BSA 함유, -20°C 보관.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 4–6 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-SAFNFGTVPSNN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2932674 |
Product Specific Information
- Recognizes isoform 1 (NP_006381.2) and isoform 2 (NP_001177924.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
- Preliminary analysis showed no signal in Western Blot.
Target Information
Importin 8 is a 1037 amino acid nuclear protein with a RAN binding site. It belongs to the RAN-binding protein superfamily and shares an N-terminal sequence motif with importin-beta that accounts for RAN GTP binding. Importin 8 binds to the nuclear pore complex (NPC) and mediates nuclear import of ribosomal proteins with a classical nuclear localization signal. It functions with RANGTP and RANBP1 to inhibit GAP stimulation of RAN GTPase and assists in nuclear import of SRP19 along with transportin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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