Thermo Fisher Scientific GPRC6A Polyclonal Antibody
GPRC6A 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체. 인간 및 비인간 영장류에 반응하며 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성을 제공. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GPRC6A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551181 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Monkey, Marmoset (100%)
Dog, Hamster, Elephant (82%)
Target Information
GPRC6A is an Orphan-U GPCR with an unknown ligand. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. Various activating ligands influence GPCR conformation, leading to signaling via G-proteins and downstream effectors. Studies also highlight mechanisms of negative regulation of GPCRs, which have significant physiological implications and drive pharmacological research for new drug candidates. Notable GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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