Thermo Fisher Scientific NK1.1/CD161c/Klrb1c Monoclonal Antibody (PK136)
Mouse NK1.1/CD161c/Klrb1c 단백질을 인식하는 PK136 클론 단일클론 항체. ICC/IF, Flow Cytometry, Functional Assay에 사용 가능. Unconjugated 형태로 제공되며, Protein A/G로 정제된 액상 제품. 마우스 반응성, 인간에는 반응하지 않음.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 0.5–1 µg/10^6 cells |
| Functional Assay | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PK136 |
| Immunogen | Mouse spleen and bone marrow cells enriched for NK-1+ cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Does not react with Human.
Target Information
NK1.1 (Killer cell lectin-like receptor subfamily B, member 1, KLRB1, NKR-P1A, CD161) is expressed on Natural Killer (NK) cells, which mediate cytotoxicity and cytokine secretion upon immune stimulation.
KLRB1 belongs to the C-type lectin superfamily and contains extracellular motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain.
NKR-P1A (encoded by KLRB1) recognizes Lectin Like Transcript-1 (LLT1) as its functional ligand.
It is classified as a type II membrane protein with an external C terminus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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