Thermo Fisher Scientific Phospho-EphA1 (Tyr605) Polyclonal Antibody
인산화된 Tyr605 부위를 인식하는 Phospho-EphA1 폴리클로날 항체. 인간 및 생쥐 시료에 반응하며 Western blot에 적합. 고순도 정제 및 안정한 PBS/glycerol 저장용액. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHA1 (Accession P21709), corresponding to amino acid residues around phosphorylated Tyr605 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817523 |
Product Specific Information
Antibody detects endogenous levels of EPHA1 only when phosphorylated at Tyr605.
Target Information
EphA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family.
EPH and EPH-related receptors are involved in developmental events, particularly in the nervous system.
Receptors in the EPH subfamily typically have:
- A single kinase domain
- An extracellular region containing a Cys-rich domain and two fibronectin type III repeats
Ephrin receptors are divided into two groups based on extracellular domain sequence similarity and ligand-binding affinity (ephrin-A and ephrin-B).
EphA1 is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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