Thermo Fisher Scientific Integrin alpha 4 Monoclonal Antibody (OSX14)
Integrin alpha 4 단백질을 인식하는 마우스 단클론 항체(OSX14). IHC에 적합하며 인간 시료에 반응. 비결합형, 동결건조 형태로 제공. 장기 보관 시 -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
Publications: 1 publication available on PubMed.
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OSX14 |
| Immunogen | Integrin alpha 4 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: Integrin alpha 4.
Target Information
Integrin alpha 4 (also known as CD49d and ITGA4) is a member of the integrin alpha chain family. Integrins are heterodimeric membrane proteins composed of alpha and beta subunits. The alpha4 chain pairs with either beta1 or beta7 chains. Ligand-binding sites of integrin alpha4β1 and alpha4β7 are located on the alpha4 chain, binding to ligands such as MadCAM, VCAM, and fibronectin. MadCAM is the principal ligand for integrin alpha4β7. HIV-1 envelope proteins can mimic MadCAM by binding to and signaling through integrin alpha4β7, the gut mucosal homing receptor for peripheral T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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