Thermo Fisher Scientific MAPKAPK3 Polyclonal Antibody
MAPKAPK3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 Immunocytochemistry에 사용 가능. 인간과 마우스 반응성, 고순도 항원 친화 크로마토그래피 정제. 액상 형태, 장기 보관 시 -20°C 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:20,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 89–382 of Human MAPKAP Kinase 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545675 |
Product Specific Information
- Recommended positive controls: H1299, HeLaS3, mouse spleen
- Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (85%), Pig (98%), Chicken (93%), Rhesus Monkey (100%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MAPKAPK3 functions as an integrative element of signaling in both mitogen and stress responses. It acts as a mitogen-activated protein kinase (MAP kinase)-activated protein kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), serve as integration points for multiple biochemical signals. MAPKAPK3 is activated by growth inducers and stress stimulation. In vitro studies show that ERK, p38 MAP kinase, and Jun N-terminal kinase can phosphorylate and activate this kinase, indicating its role in integrating mitogen and stress signaling pathways. MAPKAPK3 interacts with, phosphorylates, and represses E47, a transcription factor involved in tissue-specific gene expression and cell differentiation.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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