Thermo Fisher Scientific TSH-Receptor, B-Chain Monoclonal Antibody (TSHRB, 1405)
TSH 수용체 B-Chain을 인식하는 mouse monoclonal antibody. 인체 시료에 반응하며 IHC(P) 실험에 적합. 고순도 Protein A/G 정제, 무보존제 PBS 용액 형태. 연구용으로만 사용 가능.
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- 7253-MSM5-P1ABX
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Thermo Fisher Scientific TSH-Receptor, B-Chain Monoclonal Antibody (TSHRB, 1405)
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1–2 µg/mL
Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TSHRB, 1405 |
| Immunogen | Recombinant human TSHR, B-Chain protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
The TSH Receptor gene encodes a membrane protein that plays a major role in thyroid cell metabolism.
It serves as a receptor for thyrotropin and thyrostimulin, with activity mediated by adenylate cyclase.
Defects in this gene are associated with several types of hyperthyroidism.
Three transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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