Thermo Fisher Scientific PSG1 Polyclonal Antibody
인간 PSG1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ELISA에 적합합니다. 보존제가 포함되지 않아 필요 시 sodium azide 첨가를 권장합니다. Protein A 및 항원 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PSG1/PS-beta-G-1 Protein (Met1–Pro419) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788209 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human PSG1/PS-beta-G-1.
Target Information
Human pregnancy-specific glycoproteins (PSG) are a group of closely related secreted glycoproteins highly expressed in placental syncytiotrophoblast cells of fetal origin. PSGs are also expressed in tumors of trophoblast origin such as hydatidiform mole and choriocarcinoma. They represent the most abundant fetal protein in maternal blood at term.
The eleven human PSG genes (PSG1–PSG11) form, together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes, the CEACAM gene family. PSG stimulates secretion of TH2-type cytokines from monocytes, and CD9 has been identified as the monocyte receptor for murine PSG17. PSGs are thought to modulate the maternal immune system during pregnancy, protecting the semiallotypic fetus from rejection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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