Thermo Fisher Scientific GSC2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GSC2 protein for research use. Validated in Western blot at 1:500–1:1,000 dilution. Unconjugated, liquid form, concentration 1 mg/mL. Suitable for studies on VCFS/DGS-related developmental pathways.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human GSC2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2555125 |
Target Information
Goosecoidlike (GSCL) resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is phenotypically related to DiGeorge syndrome (DGS), and both syndromes are associated with hemizygous 22q11 deletions. Many tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, suggesting that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology.
GSCL, a homeodomain-containing gene, is expressed in a limited number of adult tissues as well as in early human development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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