Thermo Fisher Scientific IDO Recombinant Superclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Pig, Horse, and Goat.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple different recombinant monoclonal antibodies, offering the sensitivity of polyclonal antibodies and the specificity of monoclonal antibodies, with the consistency only recombinant technology can provide.

While functionally similar to polyclonal antibodies—recognizing multiple epitopes and providing higher sensitivity for low-abundance targets—Superclonal™ antibodies are composed of a defined mixture of light and heavy chains, ensuring reproducible performance across lots.

Note: Formerly called “Recombinant Polyclonal Antibody”, this product is now branded as “Recombinant Superclonal™ Antibody”. The physical product and performance remain unchanged.

Target Information

IDO1 (Indoleamine 2,3-dioxygenase 1) is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring in tryptophan, serotonin, and melatonin. This reaction initiates the production of biologically active metabolites known as kynurenines.

IDO1 is expressed in various human tissues, macrophages, and dendritic cells. Its expression is induced by interferons (IFNs), particularly IFN-gamma, as part of antimicrobial defense mechanisms. Tryptophan degradation by IDO1 inhibits the growth of viruses, bacteria, and parasites. Additionally, IDO1 plays a key role in immune regulation during infection, pregnancy, autoimmunity, transplantation, and cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.