Thermo Fisher Scientific BCL2L12 Polyclonal Antibody
Human BCL2L12 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 항-apoptotic 관련 연구에 유용. 장기보관 시 -20°C에서 안정적 유지.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BCL2L12. Recombinant protein control fragment (Product #RP-92039). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638506 |
Product Specific Information
Immunogen sequence:
PSESPRPCSL PIRPCYGLEP GPATPDFYAL VAQRLEQLVQ EQLKSPPSPE LQGPPSTEKE AILRRLVALL EEEAEVINQK
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 86%
Target Information
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2).
The encoded protein functions as an anti-apoptotic factor that inhibits caspases 3 and 7 in the cytoplasm.
In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes.
Overexpression has been detected in various cancers.
A pseudogene exists on chromosome 3.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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