Thermo Fisher Scientific FANCF Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.

This antibody is directed against human FANCF protein. A BLAST analysis indicates cross-reactivity with FANCF protein from human and chimpanzee based on 100% homology with the immunizing sequence. Reactivity with homologues from other species is not known.

Target Information

The Fanconi anemia complementation group includes FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ, FANCL, FANCM, and FANCN. The previously defined group FANCH is identical to FANCA.

Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of this complementation group assemble into a common nuclear protein complex. The FANCF gene encodes the protein for complementation group F.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.