Thermo Fisher Scientific STYXL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human STYXL1. Recombinant protein control fragment (Product #RP-91559). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:STYXL1,uniProtId:Q9Y6J8-1,ncbiNodeId:9606,antigenRange:2-103,antigenLength:313,antigenImageFileName:PA5-62159_STYXL1_Q9Y6J8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62159_STYXL1_Q9Y6J8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648064

Product Specific Information

Immunogen sequence: PGLLLCEPTE LYNILNQATK LSRLTDPNYL CLLDVRSKWE YDESHVITAL RVKKKNNEYL LPESVDLECV KYCVVYDNNS STLEILLKDD DDDSDSDGDG KD

Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 63%.

Target Information

Catalytically inactive phosphatase (PubMed:20180778, PubMed:23163895). By binding to G3BP1, inhibits the formation of G3BP1-induced stress granules (PubMed:20180778, PubMed:23163895). Does not act by protecting the dephosphorylation of G3BP1 at Ser-149 (PubMed:23163895). Inhibits PTPMT1 phosphatase activity (PubMed:24709986). By inhibiting PTPMT1, positively regulates intrinsic apoptosis (PubMed:21262771). May play a role in the formation of neurites during neuronal development (PubMed:29250526). [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.